Monday 12 January 2015

Comparative study of Tab ‘Asanad’of Ayurved Rasashala & Trivanga Bhasma in the treatment of Madhumeha


Title: Comparative study of Tab ‘Asanad’of Ayurved Rasashala  & Trivanga Bhasma in the treatment of Madhumeha

          This dissertation had submitted to the Pune University in 1996-97 for the P.G. degree M.D. (Chikitsa) & guide was Prof. Dr. P. H. Kulkarni & Research center was Tilak Ayurved Mahavidyalaya, Pune (M.S.) India.

In this research work researcher tried to compare Asanad (Proprietary product of Ayurved Rasashala, Pune) & Trivanga Bhasma in the treatment of Diabetes mellitus (Madhumeha).

          For this study 36 patients had enrolled, having age more than 30 year. Signs & symptoms of D.M. were noted & blood sugar test was done. Fasting & post prandial blood sugar were done before starting the treatment, in the middle of treatment & after the treatment. The drug was given for three months duration & follow up was taken every after 15 days. The dose of Asanad & the dose of Trivanga Bhasma was 1tds with lukewarm water
(Each tablet of 125 mg).

          In addition to Clinical trials animal experiment was also done. It is seen that Asanad reduces blood sugar levels of diabetic mice. But it dose not cause hypoglycemia in a normal mouse. LD 50 of trivanga is 16.35 gm per kg & LD 50 of Asanad is greater than 31.419 gm per kg.

          After data analysis clinical trials are conducted as follows –
After Giving Tab Asanad 125 mg (Ayurved Rasashala) 1 TDS with Luke warm water for 3 months to 1 group & giving Tab Trivanga Bhasma  ( 125 mg) 1 TDS
i)                   Asanad lowers blood sugar levels significantly, fasting by 35.79%, PP by 23.08%.
ii)                Trivanga bhasma also lowers down  blood sugar levels
                Fasting by 26.14%, PP by 21.41%.

iii)              Asanad lowers blood sugar level 10% more than that of trivanga bhasma & gives 25% more symptomatic relief to the patients
iv)              Asanad acts better by 25% for other symptoms like thirst, excessive sweating than trivanga bhasma.
v)                Asanad is more useful by 55% in bowel disturbances than trivanga bhasma.

vi)              Trivanga bhasma is more useful by 40% in urinary tract symptoms than Asanad.

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